Table 2.

Clinical and histopathological details of the 21 LPTA cases

				Calcium (mmol/l)
Case no.	Age (years)	Sex (M/F)	Tumor weight (g)	Total	Ionized	P-PTH (ng/l)	Original diagnosis	Dominating cell type	Histopathological features of atypical adenoma
1	75	F	6.54	2.85	–	711	Atypical adenoma	Chief cell	Trabecular
2	36	F	4.86	3.08	–	83	Adenoma	Chief cell	No
3	62	F	5.07	3.00	1.55	424	Adenoma	Chief cell	No
4	41	M	4.28	2.82	–	149	Adenoma	Chief cell	Trabecular
5	57	F	8.50	2.97	1.59	358	Adenoma	Chief cell	No
6	58	F	7.60	3.19	1.86	351	Adenoma	Chief cell	No
7	66	M	5.51	3.12	1.74	256	Adenoma	Chief cell	No
8	74	F	6.06	3.16	1.78	298	Adenoma	Chief cell	No
9	83	F	4.67	2.56	1.48	–	Adenoma	Oxyphilic	No
10	65	F	7.50	2.92	1.41	147	Adenoma	Chief cell	Pleomorphism
11	72	M	12.30	3.00	1.63	1070	Adenoma	Mixed	Trabecular
12	59	M	11.60	3.12	1.85	1280	Atypical adenoma	Chief cell	Capsular engagement
13	69	M	10.00	2.66	1.62	1400	Atypical adenoma	Mixed	Pleomorphism
14	54	F	13.50	3.19	1.85	245	Adenoma	Chief cell	Trabecular
15	38	F	7.00	2.81	1.58	248	Adenoma	Mixed	No
16	78	F	4.12	2.72	1.55	142	Adenoma	Chief cell	No
17	64	F	4.50	2.95	1.61	356	Adenoma	Oxyphilic	No
18	83	M	7.10	2.92	1.68	200	Adenoma	Chief cell	No
19	37	M	4.07	2.60	1.43	123	Adenoma	Chief cell	No
20	51	F	27.80	3.13	1.67	513	Adenoma	Chief cell	Trabecular
21	66	M	9.75	3.10	1.72	506	Adenoma	Chief cell	Fibrous bands

Age refers to age at diagnosis; M, male; F, female; –, not available; P-PTH, plasma parathyroid hormone. Reference values: glandular weight 0.04–0.06 g; total plasma calcium 2.15–2.55 mmol/l; ionized serum calcium 1.15–1.33 mmol/l; serum-PTH 10–65 ng/l.