Table 2.
Patient characteristics by region and uric acid concentration
| Patient Characteristics (mean or %) | Europe |
Japan |
||||
|---|---|---|---|---|---|---|
| Uric Acid >8.2 mg/dl (n = 349) | Uric Acid ≤8.2 mg/dl (n = 2642) | Uric Acid unavailable (Unavailable = 1117) | Uric Acid >8.2 mg/dl (n = 571) | Uric Acid ≤8.2 mg/dl (n = 1075) | Uric Acid unavailable (Unavailable = 73) | |
| Age (years) (mean) | 57.6 ± 15.7 | 63.5 ± 14.4 | 63.5 ± 14.9 | 59.5 ± 12.1 | 61.8 ± 13.7 | 61.0 ± 10.3 |
| Body mass index (mean) | 24.5 ± 4.6 | 24.1 ± 4.5 | 24.3 ± 4.7 | 20.8 ± 3.2 | 20.4 ± 3.0 | 20.2 ± 2.5 |
| Male (%) | 63.9 | 56.8 | 57.2 | 63.2 | 57.5 | 58.9 |
| Vintage (mean) | 5.6 ± 5.9 | 5.3 ± 5.7 | 5.7 ± 6.4 | 7.6 ± 7.2 | 7.1 ± 6.6 | 8.8 ± 8.2 |
| Serum LDL cholesterol (mg/dl) (mean) | 106.0 ± 40.5 | 100.6 ± 38.5 | 96.4 ± 35.7 | 92.7 ± 31.1 | 93.5 ± 29.7 | 94.0 ± 28.7 |
| Albumin-corrected calcium (mg/dl) (mean) | 9.7 ± 1.0 | 9.7 ± 0.9 | 9.7 ± 1.0 | 9.4 ± 0.9 | 9.5 ± 1.0 | 9.2 ± 0.8 |
| Serum phosphorus (mg/dl) (mean) | 5.7 ± 1.9 | 5.3 ± 1.7 | 5.4 ± 1.9 | 6.0 ± 1.6 | 5.5 ± 1.5 | 5.3 ± 1.3 |
| Serum albumin (g/dl) (mean) | 3.9 ± 0.5 | 3.8 ± 0.5 | 3.7 ± 0.5 | 3.9 ± 0.4 | 3.8 ± 0.4 | 3.5 ± 0.4 |
| White blood cell count (103 cells per mm3) (mean) | 7.1 ± 2.2 | 6.9 ± 2.2 | 7.0 ± 2.3 | 6.1 ± 2.0 | 5.9 ± 1.8 | 6.2 ± 1.9 |
| Serum creatinine (mg/dl) (mean) | 10.2 ± 2.9 | 9.0 ± 2.5 | 9.0 ± 2.5 | 11.9 ± 2.8 | 10.7 ± 2.9 | 11.1 ± 2.4 |
| Single-pool Kt/V (mean) | 1.38 ± 0.33 | 1.41 ± 0.31 | 1.45 ± 0.30 | 1.34 ± 0.26 | 1.34 ± 0.29 | 1.48 ± 0.28 |
| nPCR (g/kg per day) (mean) | 1.19 ± 0.27 | 1.09 ± 0.26 | 1.12 ± 0.27 | 1.11 ± 0.22 | 1.00 ± 0.22 | 1.05 ± 0.16 |
| Vascular access | ||||||
| AV fistula (%) | 79.3 | 78.2 | 74.4 | 90.7 | 90.6 | 95.3 |
| graft (%) | 7.1 | 8.5 | 10.7 | 6.5 | 6.7 | 3.1 |
| catheter (%) | 13.3 | 12.4 | 14.3 | 0.9 | 1.4 | 0.0 |
| Residual renal function (%) | 35.8 | 29.0 | 29.4 | 16.6 | 17.9 | 23.1 |
| Comorbidities | ||||||
| coronary heart disease (%) | 32.4 | 33.4 | 42.9 | 24.5 | 25.5 | 26.0 |
| congestive heart failure (%) | 25.8 | 25.0 | 26.5 | 14.6 | 16.4 | 20.3 |
| cerebrovascular disease (%) | 12.7 | 16.8 | 17.9 | 12.3 | 15.9 | 6.3 |
| diabetes (%) | 19.5 | 23.1 | 21.4 | 22.5 | 30.5 | 23.4 |
| Use of allopurinol (%) | 5.2 | 5.9 | 2.1 | 10.3 | 33.0 | 7.9 |
| Use of diuretics (%) | 22.7 | 15.7 | 26.8 | 19.6 | 21.2 | 17.5 |
Based on the initial prevalent cross section of 5827 patients with duration of ESRD >3 months in DOPPS (Dialysis Outcomes and Practice Patterns Study) I (1996–2001) and II (2002–2004). nPCR, normalized protein catabolic rate; AV, arteriovenous.