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Circadian desynchronization affects the LH surge amplitude. Means ± sem of LH surges centered at their peak time (0), grouped by phase on the day of bleeding. Each group is significantly different from each other (two way ANOVA, effect of group, F = 26.71, P < 0.0001; time, F = 23.02; P < 0.0001; and the interaction, F = 2.51, P < 0.0001).
