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Bmax values ± sem and dissociation constants ± sem (n = 2–3) from competitive binding assays on transfected A-427 cells using 125I-Tyr11-SST-14
| Receptor | Bmax (fmol/mg) | Kd (nm) |
|---|---|---|
| Wild type | 3034 ± 295 | 0.59 ± 0.03 |
| D139A | 311 ± 29 | 0.28 ± 0.07 |
| D139N | 1739 ± 440 | 0.47 ± 0.01 |
| R140A | 2181 ± 110 | 0.45 ± 0.01 |
| R140 L | 957 ± 10 | 0.25 ± 0.00 |
