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. 1999 Jul 6;96(14):7650–7657. doi: 10.1073/pnas.96.14.7650

Table 1.

Inflammatory mediators that block AHPslow in vagal afferent neurons

Mediator Receptor type EC50, nM
Bradykinin B2 72
Histamine H1 2,000
Serotonin nd 300
PGD2, PGE2 nd ∼20
Leukotriene C4 nd ∼100

Bradykinin (26), histamine (27), serotonin (28), PGD2 and PGE2 (12), and leukotriene C4 (3) block the AHPslow. nd, not determined; PG prostaglandin.