Table 3.
Effects of Ca2+ channel blockers on action potential-induced inward Ca2+ currents
| Channel type | Channel blocker | Concentration μM | Reduction | n |
|---|---|---|---|---|
| T | Amiloride | 500 | 0 ± 0 | 18 |
| L | Nifedipine | 10 | 44 ± 5.6 | 9 |
| P/Q | ω-AGA IVA | 0.2 | 0 ± 0 | 2 |
| Q | ω-CTX MVIIC | 0.25 | 0 ± 0 | 6 |
| N | ω-CTX GVIA | 1 | 40 ± 4.0 | 15 |
The blocking effect of amiloride, nifedipine, ω-agatoxin (AGA) IVA, ω-conotoxin (CTX) MVIIC, and ω-conotoxin (CTX) GVIA is expressed as percent reduction in the peak amplitude of the total calcium current ± SEM. n corresponds to the number of cells for each condition.