Table 2.
GO classification of enriched biological processes in Post-M vs. Pre-M (proliferative and secretory) endometrial epithelial cells
| Category | Fisher exact P value | Genes involved in category | Percentage (involved genes/total genes) |
|---|---|---|---|
| Post-M > Pre-M (267 genes) | |||
| Immune response | 2.80E-08 | 33 | 12.3 |
| Response to wounding | 2.40E-04 | 21 | 7.9 |
| Cell death regulation | 4.20E-03 | 22 | 8.2 |
| Negative regulation of cell proliferation | 4.40E-03 | 14 | 5.2 |
| Integrin-mediated signaling pathway | 2.40E-02 | 5 | 1.9 |
| Wnt signaling pathway | 4.80E-02 | 8 | 3.0 |
| Post-M < Pre-M (749 genes) | |||
| Protein transport | 1.70E-06 | 63 | 8.4 |
| Intracellular transport | 6.20E-06 | 55 | 7.3 |
| Lipid biosynthetic process | 3.70E-05 | 32 | 4.3 |
| Protein kinase cascade | 3.90E-05 | 35 | 4.7 |
| Cell migration | 5.50E-03 | 11 | 1.5 |
| Cell cycle | 4.80E-02 | 45 | 6.0 |
| Wnt signaling pathway | 6.80E-02 | 11 | 1.5 |
Fisher exact P value for the gene-enrichment category was generated from DAVID reference gene list. Genes involved in each category indicates the number of genes enriched for that category from the input gene list. Percentage indicates the relative number of involved genes from the total number of high or low expressing genes in individual categories. For example, the percentage of immune response is 33/267 = 12.3%.