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. 2012 Apr 24;153(6):2623–2632. doi: 10.1210/en.2012-1069

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Copyright © 2012 by The Endocrine Society

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Fig. 6. — A, Relative body weight from Vip^+/+ and Vip^−/− male (n = 4–5 per group) and female mice (n = 6–7 per group) given dextran sodium sulfate (2.5% for males and 3.0% for females) in the drinking water for 10 d and administered GLP-2 (0.2 mg/kg) or vehicle once (female) or twice (male) daily. Two-way ANOVA indicated that the weight loss curves from vehicle-treated Vip^+/+ and Vip^−/− female mice were significantly different (P < 0.001). B, Disease activity index in Vip^+/+ and Vip^−/− male and female mice after 10 d of oral DS and vehicle or GLP-2 treatment. *, P < 0.05; **, P < 0.01, GLP-2- and vehicle-treated, respectively, Vip^−/− vs. vehicle-treated Vip^+/+.