Table 1.
Effects of FGF21 on survival in LPS challenged ob/ob female mice
Expt. no. | Group | n Value | Average BW | Average BG | % Survival @ 54 h | % Survival @ 168 h | Kaplan-Meier P value vs. albumin |
---|---|---|---|---|---|---|---|
1 | Albumin | 10 | 36 ± 1.4 | 215 ± 78 | 10 | nd | |
FGF21 | 10 | 36 ± 1.7 | 199 ± 68 | 50 | nd | 0.0561 | |
2 | Albumin | 10 | 40.4 ± 2.2 | 246 ± 75 | 0 | nd | |
FGF21 | 10 | 41.2 ± 2.8 | 247 ± 68 | 80 | nd | <0.001 | |
3 | Albumin | 10 | 42.3 ± 2.4 | 281 ± 72 | 0 | 0 | |
FGF21 | 10 | 42.3 ± 2.4 | 280 ± 66 | 50 | 0 | 0.0085 | |
4 | Albumin | 10 | 44.7 ± 3.8 | 239 ± 88 | 10 | 0 | |
FGF21 | 10 | 43.3 ± 1.5 | 241 ± 46 | 50 | 20 | 0.0178 |
Data shown are the means and ses for body weight (BW) and blood glucose (BG) before LPS challenge. Expt, Experiment; %, percent; nd, not determined.