Table 2.

Brain areas with decreased and increased binding (BP_ND) of GABA_A receptors in patients with Tourette syndrome (analysis used unscaled BP_ND)

Cluster size	Regions (Brodmann areas)	x	y	z	Z-value
	Brain areas with decreased BPND
607	Left and right caudate nuclei	−18	−20	19	5.93
	Right and left thalamus (dorsomedian, midline, lateral dorsal, lateral posterior, ventral anterior, ventral lateral nucleus and pulvinar)	6	−13	13	5.14
59	Left caudate nucleus	−17	6	18	4.67
144	Right insula	40	−22	21	4.48
	Right transverse temporal gyrus (BA 41)
148	Right caudate nucleus, nucleus accumbens	6	13	−1	4.35
	Left caudate nucleus, nucleus accumbens, putamen	−12	13	−7	4.32
10	Right putamen	20	12	−4	3.74
2	Right insula	34	12	10	3.64
	Brain areas with increased BPND
1155	Left pons	−12	−23	−29	4.51
	Left and right SN	−6	−22	−9	4.50
	Left periaqueductal grey
	Left and right red nuclei
	Left and right subthalamic nuclei
366	Left cerebellum, dentate nucleus, left lobules 4–5, 6, 8, 9	−10	−52	−23	3.87
93	Right posterior cingulate gyrus, sulcus calloso-marginalis (BA 31)	20	−10	44	3.86
3	Right cerebellum, dentate nucleus	10	−52	−23	3.35

Cluster size = number of voxels; x, y, z = stereotaxic coordinates in Talairach space.