Table 4.

Effects of cimetidine (100 mg/kg) or epicatechin (50 mg/kg) on gastric juice parameters in rats (n = 7) with pyloric ligation. The results are expressed as the mean ± SEM and analyzed by ANOVA followed by Dunnett's test. *P < 0.05 and **P < 0.01 compared to the vehicle group.

Route	Treatment	Gastric juice volume (mL)	[H+] mequiv/mL/4 h
Oral	Vehicle	1.22 ± 0.80	8.03 ± 1.28
	Cimetidine	1.17 ± 0.36	2.49 ± 0.47**
	Epicatechin	1.80 ± 0.55	4.56 ± 0.56*
Intraduodenal	Vehicle	3.45 ± 0.37	7.82 ± 0.45
	Cimetidine	2.08 ± 0.16**	4.20 ± 0.63**
	Epicatechin	1.82 ± 0.15**	7.64 ± 1.29