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Role of NOS2 in hyperoxia and Ang2 siRNA administered alterations in cell death regulators. The levels of mRNA encoding A1, Bcl-2, Bim, Bax, Bak, Fas, Fas-L, and caspase-3, -8, and -9 in NOS2+/+ and NOS2−/− young adult mice exposed to room air or 100% O2 for 60 hours and administered Ang2 or scrambled siRNA are shown. This figure is illustrative of a minimum of four experiments. HYP, hyperoxia (100% O2); Scram siRNA, scrambled siRNA.
