Effects of t-TUCB and Rolipram on oxylipins in the lung. (A) Major oxylipins prostaglandin E2 (PGE2), (B) 13-hydroxyoctadecadienoic acid, and (C) 5-oxo-6,8,11,14-eicosatetraenoic acid and (D) the epoxyeicosatrienoic acids (EETs)/diols ratio are shown. Data are expressed as means ± SEM for 4–8 animals/group. *P < 0.05, TS-exposed groups were significantly different from the control group. †P < 0.05, treatment group with sEHI t-TUCB was significantly different from the TS vehicle group. ‡P < 0.05, treatment group with Rolipram was significantly different from the TS vehicle group.