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. 2012 May 24;8(5):e1002713. doi: 10.1371/journal.pgen.1002713

Figure 2. Dp(11)17/+ mice (red) are also leaner and have reduced serum TC, LDL, TC/HDL ratio, and leptin.

Figure 2

(A) Less relative total fat mass (*p = 0.000088) and more relative lean mass (*p = 0.00012) was identified in Dp(11)17/+ mice with ECHO-MRI system. (B) Dp(11)17/+ animals also possess smaller epididymal white adipose tissue pad (EWAT) (*p = 0.0020). Fasting serum profile revealed (C) reduced TC (*p = 0.021), LDL (*p = 0.01), TC/HDL ratio (*p = 0.0007) and (D) reduced leptin (*p = 0.021) in Dp(11)17/+ mice. All comparisons were made with two-tailed t-test; results are expressed as mean ± s.e.m. from measurements of (A) 6 Dp(11)17/+ and 10 WT at 21–22 wks (B) 6 Dp(11)17/+, 7 WT at 41 wks (C) 5 Dp(11)17/+ and 6 WT at 20–22 wks (D) 6 Dp(11)17/+ and 4 WT of 20–21 wks.