Figure 4. Delays of pairing/synapsis in RPM mutants vary among chromosome loci.

(A) Diagram of lacO concatemer positions on chromosomes 1, 5 and 7 scored for pairing frequency. The 4R concatemer (not shown) is adjacent to the telomere. (B) Comparison of kinetics of close pairing at different sites on chromosomes 1, 4, 5 and 7. Error bars are 1 standard deviation. Pairing is most delayed in ndj1Δ with mps3-dCC and mps3-dAR appearing to have no or intermediate delays, depending on the site. With only two exceptions, mps3-dAR at 5L telomere and ndj1Δ at 7 centromere, all sites are minimally paired at t₃. Statistical analysis of summary estimates of pairing rates (see text) is in the legend to Table 1. Strains used are listed in Table S3.