Table 2. mRNA expression of E7-related genes in Hep G2 cell after the silencing of HPV 18 E7 in RT2 Profiler™ Human Apoptosis PCR Array.
| Gene names | Genbank accession no. | Description | Folds up- or down-regulation |
| BAK1 | NM_001188 | BCL2-antagonist/killer 1 | 2.48 |
| BAX | NM_004324 | BCL2-associated X protein | 2.07 |
| BCL2 | NM_000633 | B-cell CLL/lymphoma 2 | −2.30 |
| BCL2L10 | NM_020396 | BCL2-like 10 (apoptosis facilitator) | −3.05 |
| BIK | NM_001197 | BCL2-interacting killer (apoptosis-inducing) | 2.05 |
| BIRC3 | NM_001165 | Baculoviral IAP repeat-containing 3 | −2.14 |
| CARD6 | NM_032587 | Caspase recruitment domain family, member 6 | 2.05 |
| CARD8 | NM_014959 | Caspase recruitment domain family, member 8 | 2.13 |
| CASP2 | NM_032982 | Caspase 2, apoptosis-related cysteine peptidase | 2.01 |
| CASP8 | NM_001228 | Caspase 8, apoptosis-related cysteine peptidase | 2.03 |
| CASP14 | NM_012114 | Caspase 14, apoptosis-related cysteine peptidase | 3.71 |
| CIDEA | NM_001279 | Cell death-inducing DFFA-like effector a | 2.23 |
| CIDEB | NM_014430 | Cell death-inducing DFFA-like effector b | 2.12 |
| FASLG | NM_000639 | Fas ligand (TNF superfamily, member 6) | 4.00 |
| LTBR | NM_002342 | Lymphotoxin beta receptor (TNFR superfamily, member 3) | 2.04 |
| NOL3 | NM_003946 | Nucleolar protein 3 (apoptosis repressor with CARD domain) | −3.92 |
| TNFRSF10A | NM_003844 | Tumor necrosis factor receptor superfamily, member 10a | −2.06 |
| CD27 | NM_001242 | CD27 molecule | 2.29 |
| TRAF2 | NM_021138 | TNF receptor-associated factor 2 | 2.09 |
| TRAF3 | NM_003300 | TNF receptor-associated factor 3 | 2.03 |
| TRAF4 | NM_004295 | TNF receptor-associated factor 4 | 2.25 |
In 84 E7-related genes, 21 genes mRNA transcript were altered markedly compared with the negative control. Standards of eligibility: folds up- or down-regulation >2.0 and p<0.05; n = 3.