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. 2012 May 24;7(5):e38001. doi: 10.1371/journal.pone.0038001

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Northrup et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Box plot analysis of the size of non-tumorous testes in WKY/Ztm and WKY-Dnd1^ter/Ztm with wild type (+/+), heterozygous (ter/+) and homozygous (ter/ter) genotype at 3, 6 and 9 weeks of age. ter/ter testes are degenerated and significantly smaller than +/+ and ter/+ testes (***: p<0,001). (B) HE staining of wild type and homozygous ter/ter testes of WKY-Dnd1^ter/Ztm rats from 3 to 9 weeks of age.