Table 2. Clinical features of the patients with BRCA mutations.
Sample | Age (years) | Cancer Type | Age diagnosis (years) | Familial cancer history | Tumor Histological Features | Other Tumor Features a |
Patient 1 | 31 | Breast cancer | 31 | Yes | Canalicular carcinoma | ER positive, PR positive, Her2/neu positive |
Patient 3 | 42 | Ovarian cancer | 33 | No | Ovarian serous adenocarcinoma | Not reported |
Unilateral Breast cancer | 38 | Canalicular carcinoma | Triple negative | |||
Patient 15 | 37 | Ovarian cancer | 24 | Yes | Ovarian serous adenocarcinoma | Not reported |
Unilateral breast cancer (right) | 37 | Canalicular carcinoma, brisk lymphocytic infiltrate | ER positive, PR positive and Her2/neu negative Ki-67: 5% | |||
Patient 39 | 44 | Bilateral breast cancer | 27 | Yes | Canalicular carcinoma | Triple negative |
ER = estrogen receptor; PR = progesterone receptor; HER2/neu = human epidermal growth factor receptor 2; Ki-67 = antigen KI 67.