Table 4. Detection of BRCA deleterious mutations in patients.

Sample	Gene	Mutation	Type of mutation	Position (aa)	Stop position (aa)	Coverage1	Clinical relevance	BIC reported	References
Patient 3	BRCA1	c.3124_3133delAGCAATATTA	F	1042	1047	77	Yes	No	Not reported
Patient 39	BRCA1	c.2805_2808del AGAT	F	935	998	21	Yes	No	Not reported
Patient 1	BRCA2	c.5114_5117delTAAA	F	1705	1710	70	Yes	Yes	[53]
Patient 15	BRCA2	c.2639_2640delTG	F	880	888	29	Yes	No	Not reported

¹Number of reads per nucleotide.

²Types of mutations: F: frameshift; S: stop.