Figure 1.
Over-expression of PKCι in human RMS. (a) Quantitative RT-PCR shows that PRKCI is over-expressed in human ARMS and ERMS compared to normal skeletal muscle (2.5 and 3.4-fold respectively, p<0.05). (b) PRKCI DNA copy number does not account for the increased mRNA expression. (c) Protein expression of PKCι in human ARMS by immunohistochemistry (tumor cell specific). Size bar = 0.05 mm. Semi-quantitative scales are given in methods. Staining in normal skeletal muscle was rare.