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. Author manuscript; available in PMC: 2013 Jul 17.
Published in final edited form as: Oncogene. 2012 Feb 20;32(3):286–295. doi: 10.1038/onc.2012.46

Figure 2.

Figure 2

Over-expression of PKCι in mouse ARMS. (a) Quantitative RT-PCR show Prkci is over-expressed in mouse ARMS and ERMS compared to normal skeletal muscle (7.5 and 33 fold respectively, p<0.001). (b) Immunoblotting for PKCι shows high expression and activation in mouse tumors compared to matched skeletal muscle. (c) PKCι immunohistochemistry of mouse tumors. Size bar = 0.05 mm. (d) Prkci is over-expressed in mouse ARMS primary cell cultures compared to mouse myoblast C2C12. (e) Immunoblots show Par6, PKCι and phospho-PKCι expression in mouse ARMS primary cell cultures. See Supplementary Figure S2 for full length blots of Figure 2e.