Figure 4.
Inhibition of PKCι by ATM. (a) Immunoprecipitation of PKCι and Par6 showing ATM inhibits interaction of PKCι and Par6. Numbers are relative rate of PKCι/Par6. Mean ± SE were obtained from three independent immunoblottings of immunoprecipitation. Black line shows significant difference (P<0.05). (b) Invasion potential of mouse ARMS primary cell cultures with increasing concentrations of ATM. Black line shows significant difference (P<0.01). (c) Cell growth assay for mouse primary cell cultures treated with increasing concentrations of ATM. See Supplementary Figure S4 for full length blots of Figure 4a.