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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Transfusion. 2012 Feb 17;52(8):1750–1760. doi: 10.1111/j.1537-2995.2011.03531.x

Table 4.

Complication Incidence Estimated Cost
Post-operative bacterial infection 4.6% – 15.3% 23 Up to $12,980+ depending upon severity 33
Transfusion associated circulatory overload (TACO) 1–8% 1 Variable depending upon severity
Deep vein thrombosis (DVT) 2% 1 $17,114 34 – $17,512 35
Allergic Transfusion Reaction 1–3% 36 Variable depending upon severity
Increased Length of Hospital Stay 1 1.3% per unit of RBCs transfused 23 $1,000 – $1,500 per unit transfused 37
Transfusion-related Acute Lung Injury (TRALI) 0.02% 24–1.3% 25 Variable depending upon severity
Febrile Non-Hemolytic Transfusion Reactions 0.02% 26 $8602 but variable depending upon severity26
Mistransfusion/Acute Hemolytic Transfusion Reaction 0.007% 38 $5125 39 but variable depending upon severity
HIV/Hepatitis Transmission 0.0001% 40 $117,000 – $119,000 lifetime cost 41