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Effects of ryanodine (Rya) on automaticity in SN and PF. Representative transmembrane potentials recorded from SN preparation (A) and PF (B) in control and in the presence of 0.1 and 3 µmol/L ryanodine. C through F, summary data showing the effects of 0.1 and 3 µmol/L ryanodine on the rate and maximum diastolic potential (MDP) in SN (C and E) and 0.1 µmol/L ryanodine in PF (D and F). N=6 for SN and PF.
