Table 3.

MC physical interactions with other immune cells.

Cell types	MC molecule	Partner molecule	Effect on MC	Effect on partner cell	Reference
MC-DC	ICAM-1	LFA-1	↑ Ca++ influx	↑ Maturation and chemotaxis	Otsuka et al. (2011)
MC-MDSC	n.i.	n.i.	↑ Recruitment and survival	↑ Migration and suppression activity	Yang et al. (2010)
MC-NK	CXCL8	CXCR1	n.i.	↑ Recruitment	Burke et al. (2008)
	OX40L	OX40	n.i.	IFNγ production	Vosskuhl et al. (2010)
MC-Eos	CD226	CD112	↑ Degranulation	n.i.	Bachelet et al. (2006)
	CD48	2B.4	n.i.	↑Survival	Elishmereni et al. (2010)
	n.i.	n.i.	Transfer of tryptase	↑EPO and cytokine release, transfer of EPO	Minai-Fleminger et al. (2010)
MC-CD4+T	ICAM-1	LAF-1	↑ Degranulation and cytokine release	↑ Activation and proliferation	Inamura et al. (1998), Mekori and Metcalfe (1999)
	ICAM-1	LFA-1	Adhesion to endothelial cell	n.i.	Brill et al. (2004)
	LTβR	LTβR ligand	↑ Cytokine release	n.i.	Stopfer et al. (2004)
	OX40L	OX40	n.i.	↑ Activation and proliferation	Frandji et al. (1993), Fox et al. (1994)
	MHC-II	TCR	n.i.	Cell activation	Kashiwakura et al. (2004)
	ICOSL	ICOS	n.i.	Switch to IL-10 regulatory T	Gaudenzio et al. (2009), Kambayashi et al. (2009), Valitutti and Espinosa (2010), Nie et al. (2011)
MC-CD+8	MHC-I	TCR	n.i.	Cell activation	Malaviya et al. (1996)
	MHC-I	TCR	↑ Expression of co-stimulatory molecules and degranulation	Cell activation	Stelekati et al. (2009)
MC + Treg	OX40L	OX40	↓ Degranulation	↓ Suppressive activity, conversion to Th17	Gri et al. (2008), Piconese et al. (2009)
	TGFβR	TGFβ membrane-bound	↓ Degranulation, ↑ IL-6 production	↓ Suppressive activity	Ganeshan and Bryce (2012)
MC + B	CD40L	CD40	n.i.	↑ Proliferation and Ig switch	Gauchat et al. (1993), Merluzzi et al. (2010)

n.i., not investigated.