Table 2.
Results of the preparation and endoscopic findings
| Variable |
Overall |
Excluding patients with severe constipation |
P value |
|||
| A (mosapride) | B (placebo) | C (mosapride) | D (placebo) | A vs B | C vs D | |
| No. of patients | 124 | 125 | 108 | 120 | ||
| Time to first defecation (min, mean ± SD) | 55.4 ± 27.3 | 71.2 ± 28.6 | 52.9 ± 26.2 | 70.4 ± 28.9 | < 0.001 | < 0.001 |
| Frequency of defecation (times, median, quartile) | 8.3 (4-18) | 8.6 (4-18) | 8.3 (4-18) | 8.0 (4-18) | NS | NS |
| Time of bowel preparation (min, mean ± SD) | 185.1 ± 63.8 | 198.0 ± 76.5 | 178.6 ± 58.2 | 198.0 ± 76.6 | 0.11 | < 0.05 |
| Elapsed time from last fluid intake to colonoscopy (min, mean ± SD) | 154.6 ± 48.9 | 154.1 ± 48.2 | 157.1 ± 63.2 | 155.5 ± 62.1 | NS | NS |
| Cecal intubation rate, n (%) | 119 (96.0) | 124 (99.2) | 108 (100) | 120 (100) | NS | NS |
| Insertion time1 (min, median, quartiles) | 7.8 (2-55) | 8.5 (2-38) | 7.4 (2-55) | 8.5 (2-38) | NS | NS |
| Feel of peristalsis, n (%) | 20 (16.1) | 22 (17.6) | 14 (13.0) | 22 (18.3) | NS | NS |
| Amount of irrigation fluid | ||||||
| None | 67 | 65 | 57 | 62 | NS | NS |
| < 50 mL | 40 | 47 | 33 | 46 | ||
| 50-100 mL | 15 | 11 | 12 | 11 | ||
| > 100 mL | 2 | 1 | 2 | 1 | ||
| Endoscopic findings | ||||||
| Cancer | 5 | 5 | 3 | 5 | ||
| Polyps | 70 | 82 | 61 | 79 | NS | NS |
| Diverticulosis | 32 | 39 | 29 | 38 | ||
P value by the Mann-Whitney U test.
1
Insertion time was based on patients in whom the cecal portion of the colon examined. NS: Not significant.