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. 2012 May 25;3:135. doi: 10.3389/fimmu.2012.00135

FIGURE 1.

FIGURE 1

Significance of non-inherited maternal antigen in transplantation. The nomenclature of the HLA haplotype is patient-oriented in the transplantation field. Children inherit one haplotype from each of parent. Siblings of the patient share one haplotype with the donor, and the other haplotype is the non-inherited haplotype. The HLA haplotypes in parentheses are shown as representative examples. When the patient is transplanted with donor from one of the parents or from a haploidentical sibling, the non-inherited maternal HLA antigens (NIMA) or non-inherited paternal HLA antigens (NIPA) are the mismatched haplotype. The NIMA and NIPA-mismatched siblings can be potential donors.