TABLE 2.

Significant Differential Expression of the miR-17-92 Cluster in MYC-Amplified AS Compared to MYC-unamplified AS, Other Vascular Tumors, WDLPS and DDLPS

	Mean clone count		Frequency of cloning (log scale)
MicroRNA	MYC-amplified AS	MYC-unamplified AS	MYC-amplified AS	MYC-unamplified AS	FC	FDR
hsa-miR-17-92 cluster	36,687	15,609	6.54E−02	1.48E−02	4.4	4E−02
hsa-miR-17	12,999	5,137	2.3E−02	6.7E−03	3.4	1.8E−02
hsa-miR-18a	4,160	1,334	7.7E−03	1.3E−03	5.7	3.3E−02
hsa-miR-19a	10,107	4,744	1.9E−02	5.3E−03	3.6	1.2E−01
hsa-miR-20a	9,357	4,344	1.6E−02	4.2E−03	3.8	3.5E−02
hsa-miR-92a	19	5	3.8E−05	1.3E−05	2.8	4.4E−02

MicroRNA	MYC-amplified AS	Other vascular tumors	MYC-amplified AS	Other vascular tumors	FC	FDR
hsa-miR-17-92 cluster	36,687	7,908	6.54E−02	6.89E−03	9.5	4.4E−04
hsa-miR-17	12,999	2,606	2.29E−02	2.32E−03	9.8	1.1E−03
hsa-miR-18a	4,160	609	7.68E−03	5.24E−04	14.6	5.8E−04
hsa-miR-19a	10,107	2,305	1.89E−02	2.01E−03	9.4	2.2E−03
hsa-miR-20a	9,357	2,326	1.59E−02	1.98E−03	8.0	5.1E−03

MicroRNA	MYC-amplified AS	WDLPS	MYC-amplified AS	WDLPS	FC	FDR
hsa-miR-17-92 cluster	36,687	2,551	6.54E−02	5.4E−03	12.1	2.2E−07
hsa-miR-17	12,999	277	2.3E−02	4.7E−04	48.4	2.8E−12
hsa-miR-18a	4,160	158	7.7E−03	2.9E−04	26.3	1.8E−08
hsa-miR-19a	10,107	1,374	1.9E−02	3.1E−03	6	7.7E−04
hsa-miR-20a	9,357	742	1.6E−02	1.5E−03	10.8	4.8E−06
hsa-miR-92a	19	0	3.8E−05	0	NA	2.9E−10

MicroRNA	MYC-amplified AS	DDLPS	MYC-amplified AS	DDLPS	FC	FDR
hsa-miR-17-92 cluster	36,687	2,551	6.54E−02	5.4E−03	12.1	2.2E−07
hsa-miR-17	12,999	549	2.3E−02	5.9E−04	39	2.6E−06
hsa-miR-18a	4,160	274	7.7E−03	3.3E−04	23.1	5.2E−05
hsa-miR-20a	9,357	1,444	1.6E−02	1.7E−03	9.4	1.9E−03

FC: fold-change; FDR: false discovery rate.