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Representative day 46 histology for Study 1. Consistent with the quantitative data, implanted 4.0-mm-diameter scaffolds showed no cellular infiltration or matrix formation (A). Implanted 5.0-mm scaffolds showed numerous matrix-rich chondrocyte clusters (B). For the 6.0-mm scaffolds, no chondrocytes were found in the scaffold but also the cartilage showed collagen degradation at the interface region (C). Scale bar=200 μm. Color images available online at www.liebertonline.com/tea
