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. 2012 Jan 19;23(5):460–472. doi: 10.1089/hum.2011.063

FIG. 3.

FIG. 3.

Muscle function testing after AAV vector administration. GAA-KO mice were treated with AAV2/8-LSPhGAA (n=4), AAV/2/9-CBhGAA (n=3), or dual vector administration (n=5). Means and standard error are shown. (A) Grip-force at 9 months of age for vector-treated mice. (B) Wire-hang latency at 9 months of age for vector-treated mice. (C) Open field testing of 15-min duration was analyzed at 9 months of age for vector-treated mice. GAA-KO mice were treated with AAV2/8-LSPhGAA (n=4), AAV/2/9-CBhGAA, or dual vector administration (n=5). Shown is time in motion during open field testing. (D) Distance traveled during open field testing. (E) Time in cage corners during open field testing.