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. 2012 Jan 19;23(5):460–472. doi: 10.1089/hum.2011.063

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Copyright 2012, Mary Ann Liebert, Inc.

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FIG. 6. — Differential activation of inflammatory genes in liver by AAV-LSPhGAA or AAV-CBhGAA. Mice were injected intravenously with AAV-LSPhGAA or AAV-CBhGAA or left uninjected as controls (four per group). At 8 weeks of age, liver and spleen were collected and snap-frozen. Total RNA was extracted for analysis of expression of select cytokine and chemokine genes by real-time PCR. (A) Expression of GM-CSF in spleen. (B) Expression of GM-CSF in liver. (C) Expression of IFN-γ in spleen. (D) Expression of IFN-γ in liver. (E) Expression of IL-12β in spleen. (F) Expression of IL-12β in liver. Means and standard deviation are shown.