Table 1. TP53 sequencing results of 62 patients with primary localized (n = 40) or metastastic (n = 22) GIST: P72R-polymorphism status.
Amino Acid 72 | GIST (n = 62) | % | Healthy Population* (n = 107) in % |
Arg (R) homozygous | 36 | 58 | 22 |
Pro/Arg heterozygous | 21 | 34 | 65 |
Pro (P) wildtype | 5 | 8 | 12 |