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| Stage/tissue | no.pts (n = 62) | Mutation | % | Polymorphism (P72R) | % |
| very low | 5 | 0 | 0% | 5 | 100% |
| low | 10 | 0 | 0% | 10 | 100% |
| moderate | 9 | 1 (H193R) | 11% | 8 | 89% |
| high | 16 | 0 | 0% | 14 | 87% |
| metastatic | 22 | 1 (H290P) | 5% | 20 | 91% |
