Table 2. Stratified analysis of the performance of cholera dipstick test according to fluid management (oral rehydration or intravenous fluids) in 592 patients and recent antibiotic intake (yes or no) in 576 patients.
Sensitivity (95%CI)* (TP/(TP+FN)) | Specificity (95%CI)* (TN/(TN+FP)) | PPV (95%CI)* (TP/(TP+FP)) | NPV (95%CI)* (TN/(TN+FN)) | No. pos./total (%) with V. cholerae isolated on stool culture | |
Fluid management (n = 592) | |||||
Oral rehydration n = 210 | 93.8 (79.2–99.2) (30/32) | 53.9 (46.3–61.4) (96/178) | 26.8 (18.9–36.0) (30/112) | 98.0 (92.8–99.8) (96/98) | 32**/210 (15.2) |
Intravenous rehydrationn = 382 | 92.7 (87.6–96.1) (153/165) | 42.9 (36.2–49.7) (93/217) | 55.2 (49.2–61.2) (153/277) | 88.6 (80.9–94.0) (93/105) | 165**/382 (43.2) |
p | 0.97 | 0.19 | <0.01 | 0.62 | <0.01 |
Recent antibiotic (AB) intake (n = 576) | |||||
AB received n = 58 | 93.8 (69.7–99.8) (15/16) | 59.5 (43.3–74.4) (25/42) | 46.9 (29.1–65.3) (15/32) | 96.2 (80.4–99.9) (25/26) | 16/58 (27.6) |
No AB received n = 519 | 92.8 (87.8–96.2) (155/167) | 49.3 (43.9–54.7) (173/351) | 46.5 (41.1–52.1) (155/333) | 93.5 (86.1–94.7) (173/190) | 167/518 (32.2) |
p | 0.98 | 0.48 | 0.98 | 0.86 | 0.60 |
using exact method.
in 6/203 culture positive cases no rehydration treatment was provided.