Table 1. Genotype×gender interaction analysis of common GAD1 alleles associated with panic disorder.
SNP | Alleles | Discovery | Replication | Combined | |||
rs ID | minor/major | OR | p | OR | p | OR | p |
rs1978340 | A/G | 0.519 | 0.032 | 1.292 | 0.406 | 0.832 | 0.390 |
rs3791878 | T/G | 0.578 | 0.067 | 1.443 | 0.241 | 0.938 | 0.764 |
rs3762555 | C/G | 1.872 | 0.041 | 1.446 | 0.279 | 1.496 | 0.068 |
rs3749034 | A/G | 1.992 | 0.023 | 1.445 | 0.291 | 2.009 | 0.045 |
rs2270335 | T/C | 1.713 | 0.073 | 4.060 | 0.429 | 1.398 | 0.121 |
rs2241165 | C/T | 1.958 | 0.030 | 1.325 | 0.411 | 1.483 | 0.076 |
rs11542313 | C/T | 0.979 | 0.936 | 0.691 | 0.226 | 0.826 | 0.332 |
rs3828275 | T/C | 0.780 | 0.365 | 0.607 | 0.101 | 0.718 | 0.096 |
rs2058725 | C/T | 1.763 | 0.058 | 1.296 | 0.438 | 1.472 | 0.074 |
rs701492 | T/C | 0.745 | 0.338 | 0.909 | 0.760 | 0.828 | 0.380 |
rs16858996 | G/A | 0.624 | 0.294 | 1.565 | 0.412 | 0.965 | 0.914 |
rs17701824 | T/C | 1.072 | 0.795 | 1.067 | 0.823 | 1.032 | 0.870 |
rs4439928* | G/A | 0.435 | 0.098 | --- | --- | --- | --- |
rs4439928 did not meet the quality criteria in the replication sample.
Nominally significant results are shown in bold. Abbreviations: OR, odds ratio; p, p-value; SNP, single nucleotide polymorphism.