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. Author manuscript; available in PMC: 2013 May 22.
Published in final edited form as: Curr Biol. 2012 Apr 26;22(10):843–851. doi: 10.1016/j.cub.2012.03.058

Figure 7. Model for Lrmp function in early zebrafish development.

Figure 7

(A, B) At fertilization, Lrmp protein localizes to pronuclear membranes and lrmp mRNA accumulates at centrosomes. Lrmp facilitates the association of pronuclei to the sperm aster (black arrows indicate direction of hypothesized minus-oriented motor movement), promoting pronuclear congression and fusion (C). (D) Spindle-associated lrmp mRNA may provide a localized source of newly synthesized Lrmp protein to the reforming nuclear membranes in late mitosis.