Table 2.
Mean values (SEM) of dependent measures of Tower of London (ToL) after placebo and methylphenidate 10, 20 and 40 mg (PLA, M10, M20 and M40, respectively)
| T160 | |||||
|---|---|---|---|---|---|
| PLA | M10 | M20 | M40 | ||
| Slope | 0.4 (0.0) | 0.4 (0.0) | 0.4 (0.3) | 0.4 (0.0) | |
| 2 steps | RT | 4,277 (300) | 4,356 (366) | 4,458 (418) | 4,760 (508) |
| % correct | 95.8 (2.3) | 95.9 (2.1) | 95.1 (1.6) | 94.9 (2.3) | |
| 3 steps | RT | 6,039 (502) | 6,461 (333) | 5,835 (446) | 6,128 (583) |
| % correct | 95.5 (1.4) | 95.1 (1.9) | 98.9* (0.7) | 94.5 (1.5) | |
| 4 steps | RT | 9,416 (895) | 9,197 (861) | 8,636 (715) | 9,892 (1,153) |
| % correct | 91.6 (2.3) | 89.6 (2.1) | 93.5 (2.2) | 94.3 (2.7) | |
| 5 steps | RT | 13,458 (1007) | 15,770 (1,231) | 15,076 (1,321) | 15,441 (1,291) |
| % correct | 84.1 (3.3) | 85.3* (3.0) | 79.8 (2.7) | 85.4** (3.3) | |
RT Response time
* p < 0.05; ** p < 0.1