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. Author manuscript; available in PMC: 2013 Jun 15.
Published in final edited form as: Biochem Pharmacol. 2012 Mar 7;83(12):1613–1622. doi: 10.1016/j.bcp.2012.02.028

Fig. 2. Effect of GW583340 or GW2974 on the accumulation of [3H]-MX and [3H]-paclitaxel.

Fig. 2

The accumulation [3H]-MX (A) in empty vector transfected HEK293/pcDNA3.1, ABCG2 vector transfected wild-type ABCG2-482-R2, and mutant ABCG2-482-T7 or [3H]-paclitaxel (B) in parental KB-3-1 and ABCB1 overexpressing KB-C2 cells was measured as described in Materials and Methods. Columns are the mean of triplicate determinations; bars, SD. *, P < 0.05 versus the control group. Experiments were done three independent times, and a representative experiment is shown.