. Author manuscript; available in PMC: 2012 May 27.

Published in final edited form as: Mod Pathol. 2011 Jul 8;24(11):1511–1520. doi: 10.1038/modpathol.2011.111

Table 4.

Association between increasing ratio of the number of tissue microarray spots positive for ERG fusion with the number of spots assessed and risk of prostate cancer recurrence following radical prostatectomy for clinically localized prostate cancer, 172 cases and 172 matched controls nested in the Johns Hopkins prostatectomy cohort

Fusion status	Odds ratio (95% confidence intervals)^a	P-value
Any fusion event	0.62 (0.39–1.00)	0.05
Fusion due to deletion event	0.68 (0.38–1.20)	0.18
Fusion due to split event	0.64 (0.39–1.03)	0.07
Duplicated fusion due to 2+ split events	0.99 (0.21–4.61)	0.99
Duplicated fusion due to 2+ deletion events	1.12 (0.49–2.56)	0.80
ERG gene copy number gain with single split event	0.96 (0.39–2.38)	0.93
ERG gene copy number gain with single deletion event	1.07 (0.44–2.62)	0.88
ERG gene copy number gain without fusion events	2.34 (1.24–4.40)	0.01

Per 1-Unit increase in the ratio of tissue spots positive for ERG fusion to number of spots assessed and estimated from conditional logistic regression taking into account the matching factors age, race, pathological stage, and Gleason’s sum.