Table 2.
Effects of AM and MC on α-glucosidase activity.
| Concentration of extracts (μg/mL) | α-Glucosidase activity % inhibition (−) or stimulation (+)a | |||||
|---|---|---|---|---|---|---|
| Crude water Extract | Crude methanol extract | Dichloro-methane fraction | Ethyl acetate fraction | n-Butanol fraction | Water fraction | |
| 100 | (−87.36±5.32)* [−68.96 ± 5.68*] |
(−95.63 ± 6.23*) [−76.65 ± 2.36*] |
(−94.63 ± 6.65*) [−89.59 ± 2.54*] |
(−98.64 ± 7.42*) [−90.56 ± 8.54*] |
(−72.63 ± 6.12*) [−87.65 ± 6.04*] |
(−56.32 ± 2.36*) [−62.36 ± 6.54*] |
| 50 | (−76.32 ± 6.32*) [−54.36 ± 4.36*] |
(−81.26 ± 7.12*) [−59.68 ± 5.67*] |
(−74.12 ± 5.62*) [−76.63 ± 3.21*] |
(−82.36 ± 2.34*) [−79.63 ± 7.54*] |
(−52.32 ± 2.35*) [−62.38 ± 4.21*] |
(−36.32 ± 3.36*) [−52.31 ± 2.35*] |
| 25 | (−52.36 ± 4.23*) [−36.12 ± 2.54*] |
(−66.32 ± 2.36*) [−42.16 ± 2.15*] |
(−69.32 ± 4.12*) [−60.15 ± 1.68*] |
(−76.32 ± 6.32*) [−62.64 ± 6.21*] |
(−40.16 ± 1.36*) [−40.13 ± 5.32*] |
(−28.69 ± 1.12*) [−35.36 ± 3.57*] |
| 12.5 | (−32.15 ± 2.32*) [−28.69 ± 1.69*] |
(−50.19 ± 1.13*) [−35.67 ± 1.69*] |
(−52.14 ± 2.36*) [−40.19 ± 3.28*] |
(−59.32 ± 5.32*) [−40.16 ± 3.54*] |
(−36.94 ± 2.36*) [−27.68 ± 2.31*] |
(−14.32 ± 1.62*) [−26.63 ± 2.07*] |
aResults are expressed as mean percentage ± S.E.M of seven observations in each group; (% inhibition of AM); (% inhibition of MC).
The α-glucosidase inhibitory activity (%) was defined as the percentage decrease in absorbance over the control (without extract).
*Values significantly different (P < 0.05) from the control (without extract) in each group.