Table 3.
Blood glucose level in glycogen-loaded mouse after oral administration of AM, FF, and MC extracts.
Samples | Without extract | Blood glucose concentration (mg/dl)a | |||||
---|---|---|---|---|---|---|---|
Crude methanol extract | Crude water extract | Ethylacetate fraction | |||||
1 g/kg | 2 g/kg | 1 g/kg | 2 g/kg | 1 g/kg | 2 g/kg | ||
AM | 375 ± 38 | 272 ± 19* [−27.5] |
191 ± 14* [−49.1] |
266 ± 21* [−29.1] |
196 ± 13* [−47.8] |
185 ± 17* [−50.1] |
152 ± 19* [−59.4] |
FF | 386 ± 35 | 368 ± 37 [−4.7] |
352 ± 32 [−8.8] |
369 ± 35 [−4.4] |
349 ± 22 [−9.6] |
367 ± 39 [−4.9] |
359 ± 29 [−7.0] |
MC | 379 ± 48 | 219 ± 29* [−42.2] |
171 ± 39* [−54.9] |
253 ± 26* [−33.2] |
176 ± 13* [−53.6] |
162 ± 11* [−57.3] |
136 ± 15* [−64.1] |
| |||||||
Acarbose | 172 ± 19* [−55.1] |
aResults are expressed as means ± S.E.M of seven observations in each group. (% inhibition compared to respective control (without extracts added)).
*Values significantly different (P < 0.05) from the control in each group (before extract ingested). The average of blood glucose level without administration of extracts or glycogen was 157 ± 11 mg/dL. The dose of acarbose was 400 mg/kg.