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Effect of pretreatment with RM on ethanol-induced gastric ulcer in rats. The animals received 0.9% saline solution (vehicle), lansoprazole (30 mg kg−1), and RM (0.5, 1.5, and 3.0 mg kg−1); sham group represents the manipulated animals. The results are expressed as mean ± s.d. (n = 8), and statistical significance was determined by one-way analysis of variance (ANOVA) followed by Dunnett's post-hoc t test, (P < 0.05* and P < 0.001***).
