TABLE 2.
BASELINE CHARACTERISTICS
African American (n = 233) |
White (n = 795) |
||||
Characteristic | N | Mean (95% CI) | N | Mean (95% CI) | P Value |
Age, yr* | 233 | 31.9 (30.5–33.2) | 795 | 31.8 (31.1–32.5) | 0.9458 |
Male† | 233 | 95 (40.8) | 795 | 343 (43.1) | 0.5196 |
AM peak flow, L/min* | 232 | 438.5 (425.3–451.6) | 795 | 451.5 (442.9–460.2) | 0.0891 |
FEV1, L* | 233 | 2.72 (2.64–2.79) | 794 | 3.10 (3.06–3.15) | <0.0001‡ |
FEV1% predicted* | 233 | 82.8 (81.1–84.4) | 794 | 81 (79.9–82.1) | 0.0782 |
PC20, mg/ml§ | 218 | 1.24 (1–1.53) | 728 | 1.21 (1.05–1.4) | 0.8562 |
Daily symptom scores§‖ | 232 | 0.67 (0.64–0.7) | 794 | 0.75 (0.72–0.77) | 0.0001‡ |
Daily β-agonist rescue puffs§ | 229 | 1 (0.87–1.1) | 794 | 1.2 (1.13–1.31) | 0.0016‡ |
Exhaled nitric oxide, ppb§ | 125 | 16.2 (14.2–18.5) | 437 | 14.5 (13.4–15.7) | 0.1516 |
Asthma quality of life score§¶ | 202 | 5.7 (5.62–5.87) | 683 | 5.7 (5.62–5.79) | 0.5812 |
Treatment failure† | 233 | 46 (19.7) | 795 | 101 (12.7) | 0.0074‡ |
Definition of abbreviation: CI = confidence interval.
All baseline comparisons are based on unique subjects across all studies using the latest study data for subjects in multiple studies.
Analysis of variance on original data adjusted for age, body mass index, sex, center, and study except for the analysis of age, which is not adjusted for any factors.
Chi-square test, frequency (percentage) listed instead of mean (95% CI).
P value < 0.05.
Analysis of variance on log-transformed data adjusted for age, sex, center, and study.
Symptoms were rated daily on a four-point scale (0 = absent, 1 = mild, 2 = moderate, 3 = severe).
Quality of life is based on the 32-question Asthma Quality of Life Questionnaire [27], with a seven-point scale (1 = totally limited, 2 = extremely limited, 3 = very limited, 4 = moderate limitation, 5 = some limitation, 6 = a little limitation, 7 = not at all limited).