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. 2011 Dec 1;184(11):1247–1253. doi: 10.1164/rccm.201103-0514OC

TABLE 2.

BASELINE CHARACTERISTICS

African American (n = 233)
White (n = 795)
Characteristic N Mean (95% CI) N Mean (95% CI) P Value
Age, yr* 233 31.9 (30.5–33.2) 795 31.8 (31.1–32.5) 0.9458
Male 233 95 (40.8) 795 343 (43.1) 0.5196
AM peak flow, L/min* 232 438.5 (425.3–451.6) 795 451.5 (442.9–460.2) 0.0891
FEV1, L* 233 2.72 (2.64–2.79) 794 3.10 (3.06–3.15) <0.0001
FEV1% predicted* 233 82.8 (81.1–84.4) 794 81 (79.9–82.1) 0.0782
PC20, mg/ml§ 218 1.24 (1–1.53) 728 1.21 (1.05–1.4) 0.8562
Daily symptom scores§ 232 0.67 (0.64–0.7) 794 0.75 (0.72–0.77) 0.0001
Daily β-agonist rescue puffs§ 229 1 (0.87–1.1) 794 1.2 (1.13–1.31) 0.0016
Exhaled nitric oxide, ppb§ 125 16.2 (14.2–18.5) 437 14.5 (13.4–15.7) 0.1516
Asthma quality of life score§ 202 5.7 (5.62–5.87) 683 5.7 (5.62–5.79) 0.5812
Treatment failure 233 46 (19.7) 795 101 (12.7) 0.0074

Definition of abbreviation: CI = confidence interval.

All baseline comparisons are based on unique subjects across all studies using the latest study data for subjects in multiple studies.

*

Analysis of variance on original data adjusted for age, body mass index, sex, center, and study except for the analysis of age, which is not adjusted for any factors.

Chi-square test, frequency (percentage) listed instead of mean (95% CI).

P value < 0.05.

§

Analysis of variance on log-transformed data adjusted for age, sex, center, and study.

Symptoms were rated daily on a four-point scale (0 = absent, 1 = mild, 2 = moderate, 3 = severe).

Quality of life is based on the 32-question Asthma Quality of Life Questionnaire [27], with a seven-point scale (1 = totally limited, 2 = extremely limited, 3 = very limited, 4 = moderate limitation, 5 = some limitation, 6 = a little limitation, 7 = not at all limited).