TABLE 3.

CAUSES OF TREATMENT FAILURES IN AFRICAN AMERICANS AND WHITES IN ACRN STUDIES

	African American (n = 46)	White (n = 101)
Reason	N (%)	N (%)	P Value
Asthma exacerbation	21 (45.7)	61 (60.4)	0.1091
Use of inhaled, oral, parental steroids for increased asthma symptoms	20 (43.5)	60 (59.4)	0.0776
Emergency treatment or hospitalization at a medical facility for an acute asthma exacerbation	5 (10.9)	6 (5.9)	0.3205
Decreased lung function (defined as 20% fall in FEV1 from baseline or a 35% fall in peak expiratory flow from baseline on two of three consecutive [twice daily] measurements)	7 (15.2)	23 (22.8)	0.3791
Increased asthma rescue medication use (defined as use of 8 puffs per 24 h over baseline use for a period of 48 h, or ≥ 16 puffs per 24 h for 48 h)	32 (69.6)	47 (46.5)	0.0123*
Physician clinical judgment for safety reasons	16 (34.8)	50 (49.5)	0.1098

Definition of abbreviation: ACRN = Asthma Clinical Research Network.

Data are not mutually exclusive. Each individual treatment failure could have been attributable to more than one reason.

^*P value < 0.05, Fisher exact test.