Table 2.
Selected overall helical parameters of the tRNASer microhelix structure (PDB ID: 3GVN) compared to the LNA-RNA hybrid (PDB ID: 1H0Q) and the LNA helix (PDB ID: 2X2Y). The two LNA molecules correspond to two LNA helices located in the asymmetric unit of the crystal structure.
| Twist (°) | Rise (Å) | Slide (°) | Roll (°) | χ-displacement (Å) | Propeller twist (°) | |
|---|---|---|---|---|---|---|
| RNA | 32.46 | 2.64 | −1.68 | 6.61 | −4.25 | −10.46 |
| tRNASer microhelix | ||||||
|
| ||||||
| LNA-RNA | 29.22 | 2.65 | −2.24 | 6.07 | −5.40 | −12.84 |
| hybrid | ||||||
|
| ||||||
| LNA | ||||||
| (molecule A) | 25.97 | 2.81 | −2.49 | 4.08 | −6.60 | −6.65 |
| tRNASer microhelix | ||||||
|
| ||||||
| LNA | ||||||
| (molecule B) | 26.13 | 2.84 | −2.47 | 4.15 | −6.47 | −7.45 |
| tRNASer microhelix | ||||||