TABLE 4.

KEY RESEARCH PRIORITIES FOR CRITICAL CARE: BASIC SCIENCE/CELLULAR RESEARCH

1. Seek to define factors that alter a normal stress response in critical illness.

2. Investigate the role of the host response in initiation, transition, and resolution of critical illness.

3. Define the microbiome in normal individuals and investigate its role and transitions in critical illness.

4. Integrate research in the biology of tissue repair with investigation into mechanisms that underlie critical illness.