Figure 5.
Improved bacterial clearance in PTEN CKO BMT mice after P. aeruginosa pneumonia. Mice were injected intratracheally with 50 μL of 5 × 105 CFU P. aeruginosa. At 24 hours after infection, bacterial burden of whole lung (A) and blood (B) samples from each mouse was assessed by CFU assay (*P < 0.05, **P < 0.01, ***P < 0.001; n = 8–10 mice per group).