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. 2012 May 3;109(21):E1344-E1351. doi: 10.1073/pnas.1202426109

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Fig. 6. — Effects of Ca²⁺ on cubic difference products. This hair bundle was subjected to the sum of two sinusoidal forces with equal amplitudes . (A) At an endolymphatic Ca²⁺ concentration of 250 μM, the hair bundle displayed spontaneous oscillations at a characteristic frequency f_C = 19 Hz. The spectral density of hair-bundle movement is plotted for stimulation at resonance (f₁ = 18 Hz and f₂ = 19 Hz) with a stimulus amplitude . (B) When the Ca²⁺ concentration was raised to a value of 1 mM, the hair bundle became quiescent. The spectral density of motion resulted from the same stimulus as in A. (C) The arithmetic-mean level of the two cubic difference products is plotted as a function of the stimulus amplitude for f₁ = 18 Hz and f₂ = 19 Hz (black) and f₁ = 180 Hz and f₂ = 190 Hz (red). Close and open symbols correspond to oscillatory and quiescent conditions, respectively. Note the notch in the level function depicted by red disks. Data in A–C from the same cell.

Inline graphic — Effects of Ca²⁺ on cubic difference products. This hair bundle was subjected to the sum of two sinusoidal forces with equal amplitudes . (A) At an endolymphatic Ca²⁺ concentration of 250 μM, the hair bundle displayed spontaneous oscillations at a characteristic frequency f_C = 19 Hz. The spectral density of hair-bundle movement is plotted for stimulation at resonance (f₁ = 18 Hz and f₂ = 19 Hz) with a stimulus amplitude . (B) When the Ca²⁺ concentration was raised to a value of 1 mM, the hair bundle became quiescent. The spectral density of motion resulted from the same stimulus as in A. (C) The arithmetic-mean level of the two cubic difference products is plotted as a function of the stimulus amplitude for f₁ = 18 Hz and f₂ = 19 Hz (black) and f₁ = 180 Hz and f₂ = 190 Hz (red). Close and open symbols correspond to oscillatory and quiescent conditions, respectively. Note the notch in the level function depicted by red disks. Data in A–C from the same cell.