Table 5.
The genotype frequency of VEGFA/VEGFR2 genes SNPs and Hardy-Weinberg equilibrium (HWE) test results
| Polymorphism | rs number | Genotype (%) | HWE exact p value | Frequency of risk allele | ||
|---|---|---|---|---|---|---|
| Homozygous (wild) | Heterozygou | Homozygous (mutant) | ||||
| VEGFA | ||||||
| -2578 C > A | rs699947 | 32.4 | 54.1 | 13.5 | 0.73 | 0.41 |
| -460 T > C | rs833061 | 29.7 | 45.9 | 24.3 | 0.74 | 0.47 |
| 936 C > T | rs3025039 | 75.7 | 24.3 | - | 1.00 | 0.12 |
| 405 G > C | rs2010963 | 24.3 | 40.5 | 35.1 | 0.32 | 0.55 |
| VEGFR2 (= KDR) | ||||||
| 3405-92A > G | rs1531289 | 48.6 | 45.7 | 5.7 | 0.69 | 0.29 |
| 1416 T > A | rs1870377 | 53.1 | 40.6 | 6.3 | 1.00 | 0.27 |