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. Author manuscript; available in PMC: 2012 Jul 13.
Published in final edited form as: Oncogene. 2011 Nov 14;31(28):3392–3396. doi: 10.1038/onc.2011.508

Figure 2. The BimBad and BimNoxa mutations accelerated Eμ-Myc induced lymphomagenesis but the BimPuma mutation had no significant impact.

Figure 2

Analysis of lymphoma-free survival was carried out using Graph Pad Prism (version 5.0a). (a) Lymphoma-free survival of control Eμ-Myc as well as Eμ-Myc/BimBad/+, Eμ-Myc/BimBad/Bad, Eμ-Myc/BimNoxa/+ and Eμ-Myc/BimNoxa/Noxa mice. (b) Lymphoma-free survival of control Eμ-Myc as well as Eμ-Myc/BimPuma/+ and Eμ-Myc/BimPuma/Puma mice. (c) Summary of data presented in (a) and (b), showing for each genotype of mice the median survival, the number of mice analyzed and statistical analysis of difference in survival in comparison to control Eμ-Myc mice. Statistical evaluation of tumor-free survival data was undertaken using a log-rank test (Mantel-Cox) and 1-way ANOVA test on Kaplan-Meier curves.